Radioprotection on nucleated and anucleated erythrocytes by oxide-reduction coenzymes

Abstract The protective effects of NAD, FAD and Quinone and mixtures of these compounds were studied on gamma irradiated rabbit and chicken erythrocytes. The dose relative factor (DRF 37) was evaluated by visible absorbancy measurements of liberated hemoglobin. The DRF 37 obtained on rabbit erythrocytes were : NAD+FAD+Quinone mixture : 11,1; NAD+Quinone mixture : 6,1; FAD+Quinone mixture : 6,1; NAD: 1,6; FAD: 5,5; Quinone: 5,1. The DRF 37 obtained with the mixture NAD+FAD+Quinone on chicken erythrocytes was 3,9. The high efficiency of the radioprotective mixture NAD+FAD+Quinone is discussed.