生命银行
医学
民族
哮喘
人口学
横断面研究
肺功能
儿科
内科学
肺
病理
人类学
遗传学
生物
社会学
作者
John Busby,P. Jane McDowell,Paul Pfeffer,Adel Mansur,Liam G. Heaney
出处
期刊:Thorax
[BMJ]
日期:2023-12-07
卷期号:79 (2): 186-190
标识
DOI:10.1136/thorax-2023-221101
摘要
Ethnic disparities exist within asthma; however, country of birth is rarely investigated. We described demographic and clinical characteristics by ethnicity and country of birth within the UK Biobank. Lung function and asthma hospitalisations were similar for white, black and North-East Asian participants, however, South-East (SE) Asians more commonly had an FEV 1 below the lower limits of normal (LLN; 53.8% vs 32.3%, p<0.001), blood eosinophilia (38.6% vs 23.8%, p<0.001) and asthma hospitalisation (12.5% vs 8.3%, p<0.001) than white participants. First-generation SE Asian immigrants had poorer lung function (57.7% vs 27.7% FEV 1 below LLN, p<0.001) than UK/Ireland born participants. These data demonstrate inter-ethnic and intra-ethnic disparities.
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