化学
小学(天文学)
胺气处理
芳基
氧化磷酸化
铵
亲核细胞
碘
卤化
有机化学
组合化学
催化作用
烷基
生物化学
物理
天文
作者
An-Jing Wang,Yu-Die Zhang,Wen-Jing Nan,Shan Liu,Wen-Ming Shu,Yin-Xiang Gong
标识
DOI:10.1002/ejoc.202300154
摘要
Here we report the preparation of primary α-ketoamides via a highly efficient molecular iodine-mediated oxidative amidation of aryl methyl ketones with ammonium carbamodithioate. A self-sequenced iodination/nucleophilic substitution/Kornblum oxidation/amidation mechanism was proposed. In this mechanism, α-thiocyanatoacetophenone is the key intermediate.
科研通智能强力驱动
Strongly Powered by AbleSci AI