白质
疾病
医学
脂质积聚
代谢物
磁共振成像
病理
生物标志物
内科学
内分泌学
高强度
磁共振弥散成像
变性（医学）
脂质代谢
白色（突变）
磁共振弥散加权成像
作者
Amirreza Haghighi,Hamide Nasiri,Arman Ghayourvahdat,Hannaneh Azimizonuzi,Nezamaddin Ghasemi,Mohammad D. Mansouri,Arya Moftakhar Bazkiaei,Mohammad Amir Amirian,Sirous Zeinali,Hamed Gozali,Reza Rostami,Maryam Ayobi,Alzheimer's Disease Neuroimaging Initiative
摘要
Circulating lipid metabolites link to white matter integrity in early Alzheimer's disease (AD)Phosphatidylcholines (PCs), lysophosphatidylcholines (LPCs), and propionylcarnitine associate with tract-specific diffusion magnetic resonance imaging (dMRI) metricsNo metabolite-white matter associations detected in established ADPlasma metabolites may serve as biomarkers of early white matter degeneration.
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(2025-6-4)
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