Innervation of Lymph Nodes: A Combined Silver Impregnation and Electron-Microscopic Study

Using silver impregnation and electron-microscopic techniques, nerves have been demonstrated in rat axillary, cervical and inguinal lymph nodes, and their distribution was investigated. With the electron microscope, vesicle-containing varicosities or terminals are demonstrated in close proximity to reticulum cells, lymphocytes, plasmablasts and mature plasma cells. Nerves supplying the blood vessels possibly differ from those supplying stromal or lymphocytic elements.