Cryptococcus peritonitis a rare manifestation in HIV positive host: A case report

Cryptococcus neoformans is an encapsulated yeast found ubiquitously in the environment and causes serious infections in immunocompromised populations. Disseminated disease is uncommon and very rarely manifests as peritonitis. We report a case of cryptococcal peritonitis in a HIV positive patient, who presented with distention of abdomen, vomiting, and dyspnoea, where the diagnosis was made on cytological smears of ascitic fluid. The importance of making a quick diagnosis utilizing cytological smears is emphasized and the cytological features are demonstrated. Disseminated cryptococcosis, particularly with peritonitis, is an uncommon manifestation of C. neoformans infection. A high clinical suspicion and early initiation of therapy is needed to recognize and treat patients effectively.