Antioxidation in vitro of Polysaccharides with Different Molecular Weight from Lycium bararum L.

[Objective] To study the antioxidation in vitro of polysaccharides with different molecular weight from Lycium bararum.[Method] Lycium bararum polysaccharide(LBP) was extracted and separated by membrane separation technique into four parts as relative molecular weight less than ten thousand(LBP1),between ten thousand and thirty thousand(LBP2),thirty thousand and fifty thousand(LBP3) and greater than fifty thousand(LBP4).The superoxide radical scavenging effects,hydroxyl radical scavenging activity and total antioxidant capacity of the crude polysaccharides and the four parts of small molecular polysaccharides were analyzed for antioxidant activity in vitro.[Result] The antioxidant activity of the four parts of small molecular polysaccharides was higher than LBP,and the antioxidant activity of LBP2 is the highest,significantly higher than that of LBP.[Conclusion] The study provided a new method for the rational development and high-efficient utilization of LBP.