Effects of GLP-1 on vascular smooth muscle cells in vascular remodeling

Phenotypic transformation and hyperproliferation of vascular smooth muscle cells (VSMC) in vascular remodeling are important links leading to its occurrence and development. A large number of studies have found that glucagon-like peptide-1 (GLP-1) was involved in the regulation of VSMC function, and its role in vascular remodeling such as improving atherosclerosis and preventing vascular restenosis was widely concerned. Key words: Glucagon-like peptide-1; Vascular remodeling; Vascular smooth muscle cells