胆管上皮细胞
转录组
生物
细胞生物学
化学
免疫学
内分泌学
生物化学
基因表达
基因
作者
Hanyang Liu,Yin Guo,Bianca Franco Leonardi,Tian Lan,Yeni Ait Ahmed,Hilmar Berger,Marlene Kohlhepp,Natalja Amiridze,Natalia Martagón Calderón,Carla Frau,Ludovic Vallier,Milad Rezvani,Frank Tacke,Adrien Guillot
出处
期刊:Gut
[BMJ]
日期:2025-04-08
卷期号:74 (10): 1694-1710
被引量:14
标识
DOI:10.1136/gutjnl-2024-334425
摘要
This study reveals a paracrine communication circuit during ductular reaction, in which reactive cholangiocyte-derived ORM2 reprogrammes liver macrophages, participating in a pathogenic remodelling of the immune biliary niche.
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