嗜酸乳杆菌
鼠李糖乳杆菌
益生菌
抗生素相关性腹泻
抗生素
腹泻
双歧杆菌
厚壁菌
乳酸菌
生物
微生物学
肠道菌群
粪便
医学
食品科学
细菌
免疫学
胃肠病学
发酵
艰难梭菌
遗传学
16S核糖体RNA
作者
Yang Chen,Shu‐Ling Lu,Zhiwei Ye,Xin Cai,Shaoteng Wu,Pan Li,Bing Du
出处
期刊:Future Microbiology
[Future Medicine]
日期:2022-08-01
卷期号:17 (12): 943-956
被引量:2
标识
DOI:10.2217/fmb-2021-0240
摘要
Probiotics and their products are the classic way to treat and prevent gastrointestinal diseases. In this study, the authors designed new combinations and doses of probiotic beverages for antibiotic-associated diarrhea. Group S1 was different from the other groups, including Lactobacillus rhamnosus HN001, Lactobacillus acidophilus NCFM and Bifidobacterium lactis BI-07. Its inulin content was higher than those of the other groups. Mice were induced with a 16-day administration of triple antibiotics in advance for 2 weeks prior to antibiotic treatment. In the experiment, the treatment group returned to normal more quickly than the placebo group. In group S1, the relative abundance of the phylum Firmicutes and genus Lactobacillus increased, and the structure of the microbiota was the closest to normal among all groups. In conclusion, the combinations of probiotic beverages effectively caused structural recovery of the gut and fecal microbiota against antibiotic-associated diarrhea, and the S1 formula showed the best efficacy.
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