粒体自噬
疾病
线粒体
神经科学
机制(生物学)
能量代谢
细胞内
能源消耗
人口
老化
人口老龄化
医学
老年学
生物
细胞生物学
自噬
内分泌学
内科学
环境卫生
生物化学
细胞凋亡
哲学
认识论
作者
Jinglin Yao,Bohong Kan,Zhengjia Dong,Zhenyu Tang
标识
DOI:10.2174/0115672050300063240305074310
摘要
The prevalence of Alzheimer's disease (AD) is increasing as the elderly population, which hurts elderly people's cognition and capacity for self-care. The process of mitophagy involves the selective clearance of ageing and impaired mitochondria, which is required to preserve intracellular homeostasis and energy metabolism. Currently, it has been discovered that mitophagy abnormalities are intimately linked to the beginning and progression of AD. This article discusses the mechanism of mitophagy, abnormal mitophagy, and therapeutic effects in AD. The purpose is to offer fresh perspectives on the causes and remedies of AD.
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