医学
母乳
六烯酸
肥胖
脂肪酸
哺乳期
多不饱和脂肪酸
怀孕
母乳喂养
产科
生理学
内科学
儿科
生物
生物化学
遗传学
作者
Tugce Tekin-Guler,Nevra Koç,Aysun Kara-Uzun,Mehmet Fisunoğlu
出处
期刊:Breastfeeding Medicine
[Mary Ann Liebert]
日期:2023-06-01
卷期号:18 (6): 475-482
标识
DOI:10.1089/bfm.2023.0002
摘要
Objectives: This study aimed to evaluate the effect of prepregnancy obesity on fatty acid profile in breast milk, to determine the relationship between maternal diet and fatty acids in breast milk, and to investigate the relationship between fatty acids in breast milk and infant growth. Materials and Methods: Twenty normal-weight mothers, 20 obese mothers, and their infants were recruited. Breast milk samples were collected at 50-70 days postpartum. Breast milk fatty acid was analyzed with gas chromatography. Infant body weight, height, and head circumference were taken from medical records at birth and during study visits at 2 months. Dietary intake was assessed by trained dietitians using a 24-hour dietary recall method. Results: Alpha-linolenic acid (ALA, p = 0.040), docosahexaenoic acid (DHA, p = 0.019), and total n-3 fatty acid (p = 0.045) in total milk were found to be higher in normal-weight mothers compared with obese mothers. A positive association was found between C20:4 n-6 in foremilk and weight for age percentile (r = 0.381, p = 0.031; β = 29.966, p = 0.047). Conclusions: Prevention of prepregnancy obesity is important for future generations, as prepregnancy obesity has many adverse effects on the mother and infant and may affect the composition of breast milk.
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