More advanced drilling techniques are demanded for deep ore exploration.The deeper a drilling hole is,the longer the construction period would be with more complicated situations in borehole and more difficulties in construction,so wall protection becomes more important.The paper discussed the technique of wall protection with slurry in deep-hole drilling in complicated formation with deep-hole drilling problems in recent years,and presented the test application of PHP mud and LBM mud,which could be the reference for deep-hole drilling construction.