Synthesis and characterization of 2-(2,4-dinitrophenylsulphanyl)-1H-benzimidazole derivatives

In this article we focused on the synthesis and characterization of [2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-yl]acetic acid (substituted-benzylidene) hydrazides (7a-g) and 5-[2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-ylmethyl]-[1,3,4]-oxadiazole-2-thiol (8) derived from 2-{2-[(2,4-dinitrophenyl)sulphanyl]-1H-benzimidazol-1-yl}ethanohydrazide (6). Compound 6 was achieved from 1H-benzimidazole-2-yl-(2,4-dinitrophenyl) sulphide (4) with ethyl chloroacetate followed by treatment with hydrazine hydrate. The newly synthesized compounds were characterized by elemental analysis, IR, 1H NMR and Mass spectral data.