The Clinical Study on the Freatment of Multiple Myeloma lombined by the VDA Regimen and Malphalan

Objective:To explore more effective treatment regimen for multiple myeloma (MM).Methods:Randomized clinical trial was conducted to determine whether the outcome of MM patients treated with the MVDA regimen was better than that with VDA regimen.Results:The remission rate of cases treated with MVDA regimen ( 60.8 %) was significantly higher than that of cases treated with VDA regimen ( 23.5 %) (P 0.025 );The granulocyte decreasing (GD) rate and platelet decreasing (PD) rate of cases treated with MVDA regimen were higher than that of cases treated with VDA regimen,but the time of the GD and the time of the PD were shorter than 2 weeks.Conclusion:The treatment outcome of MM was better with MVDA regimen than that with VDA regimen,The MVDA is a effective treatment regimen for MM.