Cylindrical PDMS Microchannel Fabrication by Sacrificial Molding Using Caramel

Arbitrary microchannel network was successfully produced with no costly equipment and no cytotoxic material. In our method, sacrificial caramel embedded inside solid PDMS (polydimethylsiloxane) simply dissolves to form arbitrary shaped enclosed channels. Deformation of caramel by its surface tension realizes cylinder microchannel easily.