Acoustic Screening for Obstructive Sleep Apnea in Home Environments Based on Deep Neural Networks

阻塞性睡眠呼吸暂停 多导睡眠图 医学 金标准(测试) 睡眠呼吸暂停 睡眠(系统调用) 呼吸暂停 计算机科学 呼吸 呼吸不足 听力学 心脏病学 内科学 麻醉 操作系统
作者
Hector E. Romero,Ning Ma,Guy J. Brown,Elizabeth A. Hill
出处
期刊:IEEE Journal of Biomedical and Health Informatics [Institute of Electrical and Electronics Engineers]
卷期号:26 (7): 2941-2950 被引量:41
标识
DOI:10.1109/jbhi.2022.3154719
摘要

Obstructive sleep apnea (OSA) is a chronic and prevalent condition with well-established comorbidities. However, many severe cases remain undiagnosed due to poor access to polysomnography (PSG), the gold standard for Obstructive sleep apnea (OSA) diagnosis. Accurate home-based methods to screen for OSA are needed, which can be applied inexpensively to high-risk subjects to identify those that require PSG to fully assess their condition. A number of methods that analyse speech or breathing sounds to screen for OSA have been previously investigated. However, these methods have constraints that limit their use in home environments (e.g., they require specialised equipment, are not robust to background noise, are obtrusive or depend on tightly controlled conditions). This paper proposes a novel method to screen for OSA, which analyses sleep breathing sounds recorded with a smartphone at home. Audio recordings made over a whole night are divided into segments, each of which is classified for the presence or absence of OSA by a deep neural network. The apnea-hypopnea index estimated from the segments predicted as containing evidence of OSA is then used to screen for the condition. Audio recordings made during home sleep apnea testing from 103 participants for 1 or 2 nights were used to develop and evaluate the proposed system. When screening for moderate OSA the acoustics based system achieved a sensitivity of 0.79 and a specificity of 0.80. The sensitivity and specificity when screening for severe OSA were 0.78 and 0.93, respectively. The system is suitable for implementation on consumer smartphones.
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