Magnitude of the kinetic isotope effect for the oxidative demethylation of anisole and [Me-2H3]anisole: a new and simple criterion for assessing model systems for cytochrome P450 dependent mono-oxygenases

The data from the oxidative demethylation of anisole, [Me-2H3] anisole by rat liver microsomes and ten model systems shed light on the mechanisms of O-demethylation and can be used to classify the model systems.