The vulnerability of global supply chains has been fully exposed in various emergencies in recent years. As a pillar industry of the national economy, the construction of supply chain resilience for manufacturing industry has been elevated to the national strategic level. At the same time, the in-depth development of digital technologies has provided a brand-new research paradigm and practical path for supply chain risk management. This paper systematically combs the theoretical evolution context of digital empowerment for supply chain resilience of manufacturing enterprises, constructs a triple mechanism framework of "information transparency - intelligent decision-making - relationship coordination", and extracts practical paths for supply chain resilience construction in the digital context by combining empirical research results and typical enterprise cases at home and abroad. The study finds that the impact of digitalization on supply chain resilience presents a non-linear characteristic, with significant threshold effect and context dependence. Enterprises should avoid blind technology-oriented investment, and instead focus on the coupled and coordinated development of digital capabilities and risk governance capabilities. The conclusions of this paper can provide theoretical reference and decision-making reference for the research on digital transformation of manufacturing industry and the safety and stability of industrial and supply chains.