α‐Glucosidase Inhibitory Components from Garcinia pedunculata Fruits

Abstract From Garcinia pedunculata Roxb. fruits, two undescribed aromatic compounds including a benzofuran and a depsidone derivative, and a new natural product, together with four known compounds were isolated. Through the analysis of spectroscopic data, high resolution mass spectrum and calculated nuclear magnetic resonance, their structures were determined. The α ‐glucosidase inhibitory activity of the isolates was evaluated. And compound 3 exhibited a moderate inhibitory effect on α ‐glucosidase. The molecular docking of compound 3 was performed to elucidate the interaction with α ‐glucosidase.