Quinoxaline-Based Conjugated Microporous Polymer Photoelectrochemical Sensor for the Sensitive Detection of Dopamine

Dopamine (DA) is an important central neurotransmitter and plays a significant role in both human physiology and pathology. Consequently, its rapid and sensitive detection is of considerable significance. This study demonstrates the synthesis of a novel quinoxaline-based conjugated microporous polymer (CMP) via a simple Friedel-Crafts reaction. A rapid and sensitive photoelectrochemical (PEC) sensor based on the CMP was then constructed and used for the detection of DA. Under optimal experimental conditions, the developed PEC sensor exhibited good detection ability in the linear range of 0.0125–35 μ M with a detection limit of 0.007 μ M in addition to high selectivity and good repeatability. Furthermore, this sensor enabled the detection of DA in blood serum with a good recovery rate. Therefore, this study presents a new prospective for the application of photoresponsive CMP materials in PEC sensors.