Blinatumoab公司
医学
耐火材料(行星科学)
地塞米松
淋巴瘤
内科学
弥漫性大B细胞淋巴瘤
肿瘤科
抗体
癌症研究
免疫学
材料科学
CD19
复合材料
作者
Andreas Viardot,Marie-Elisabeth Goebeler,Georg Heß,Svenja Neumann,Michael Pfreundschuh,Nicole Adrian,Florian Zettl,M. Libicher,Cyrus Sayehli,Julia Stieglmaier,Alicia Zhang,Dirk Nagorsen,Ralf C. Bargou
出处
期刊:Blood
[Elsevier BV]
日期:2016-01-12
卷期号:127 (11): 1410-1416
被引量:323
标识
DOI:10.1182/blood-2015-06-651380
摘要
Key Points Among evaluable patients with relapsed/refractory DLBCL who received blinatumomab 112 μg/d, overall response was 43% (CR was 19%). Blinatumomab continuous infusion was feasible with weekly stepwise dose escalation (9-28-112 μg/d) and dexamethasone prophylaxis.
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