Diagnostic criteria for MOGAD

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare antibody-mediated inflammatory demyelinating disorder of the central nervous system with a broad clinical spectrum. Distinct from multiple sclerosis (MS) and aquaporin-4-seropositive neuromyelitis optica spectrum disorder (AQP4-NMOSD), MOGAD can follow a monophasic or relapsing disease course and is characterised by the presence of antibodies against MOG. Until now, there had been no international consensus on diagnostic criteria for MOGAD and in this month’s journal club, we explore three recent papers on this topic.