Clinical translation of metabolomics markers in endometrial carcinoma

Abstract Objective This comprehensive review highlights the current research on metabolomics and the metabolic pathways involved in endometrial cancer (EC), offering potential non‐invasive biomarkers for EC. Methods The data was extracted from published manuscripts between 2015 and 2024 using the reputed search engine “Pubmed.” All gathered data were organized into a single table, facilitating a comparison with earlier findings. Results The results of this study revealed most metabolites identified in previous metabolomic research on EC are associated with lipid, glucose, and amino acid metabolism. Conclusion Therefore, understanding these metabolic pathway alterations in EC is crucial for improving diagnosis, prognosis, and treatments by specially targeting these metabolic pathways.