A Randomized, Open-Label Study of the Safety and Tolerability of Fospropofol for Patients Requiring Intubation and Mechanical Ventilation in the Intensive Care Unit

This pilot study suggests that fospropofol, administered in either an infusion/bolus or infusion-only regimen, is tolerable and effective for short-term induction and maintenance of sedation in mechanically ventilated intensive care unit patients.