Protection and Deprotection of Common Functional Groups

This chapter provides a summary of protection and deprotection of common functional groups applied in modern organic chemistry and drug synthesis. The functional groups covered include amines, alcohols, carboxylic acid group, carbonyl group, and terminal alkyne. Protection and deprotection of amino functional group are key steps in organic synthesis. Selective protection and deprotection of hydroxyl group are the essential steps for the synthesis of complex molecules. Protection and deprotection for the carboxylic acid group are common practice in organic synthesis. The carbonyl functional group is the backbone in organic chemistry and frequently is required the protection and deprotection of this group. The chapter is an indispensable guide for researchers and professionals in organic chemistry, natural product synthesis, pharmaceutical, and medicinal chemistry, as well as post-graduates preparing themselves for a job in the pharmaceutical industry.