Molecular mechanism of miRNA mediated biosynthesis of secondary metabolites in medicinal plants

生物合成 机制(生物学) 次生代谢物 小RNA 药用植物 次生代谢 生物化学 生物技术 鉴定(生物学) 生物 计算生物学 基因 植物 认识论 哲学
作者
Hongwei Li,Ziyi Guo,Mengwei Xu,Juanjuan Zhao,Delin Xu
出处
期刊:Plant Physiology and Biochemistry [Elsevier BV]
卷期号:208: 108524-108524 被引量:21
标识
DOI:10.1016/j.plaphy.2024.108524
摘要

Plant secondary metabolites are important raw materials for the pharmaceutical industry, and their biosynthetic processes are subject to diverse and precise regulation by miRNA. The identification of miRNA molecules in medicinal plants and exploration of their mechanisms not only contribute to a deeper understanding of the molecular genetic mechanisms of plant growth, development, and resistance to stress, but also provide a theoretical basis for elucidating the pharmacological effects of authentic medicinal materials and constructing bioreactors for the synthesis of medicinal secondary metabolite components. This paper summarizes the research reports on the discovery of miRNA in medicinal plants and their regulatory mechanisms on the synthesis of secondary metabolites by searching the relevant literature in public databases. It summarizes the currently discovered miRNA and their functions in medicinal plants, and summarizes the molecular mechanisms regulating the synthesis and degradation of secondary metabolites. Furthermore, it provides a prospect for the research and development of medicinal plant miRNA. The compiled information contributes to a comprehensive understanding of the research progress on miRNA in medicinal plants and provides a reference for the industrial development of related secondary metabolite biosynthesis.
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