Taxonomic and functional profiling of skin microbiome in psoriasis

This research utilizes whole metagenomic shotgun sequencing to analyse the skin microbiome in patients with psoriasis, comparing lesional and nonlesional skin with those of healthy individuals. The study identifies significant differences in the microbial composition and functionality between psoriatic and healthy skin, revealing distinct microbial patterns and disruptions in psoriatic skin. These findings highlight the complex role of skin microbiota in psoriasis, emphasizing variations in bacteria and their functional characteristics beyond mere species identification.