Risk Assessment of Cyclaniliprole Resistance in Peach‐Potato Aphid Myzus persicae: Laboratory Selection, Inheritance, and Cross‐Resistance Patterns

ABSTRACT Cyclaniliprole, a type of the third‐generation anthranilic diamide insecticide, was mainly used for management of various pests. Myzus persicae (Hemiptera: Aphididae), known as the peach‐potato aphid, is an economically essential pest with worldwide distribution. However, the risk assessment of cyclaniliprole in M. persicae is unclear. The cyclaniliprole risk assessment in M. persicae showed 2.56‐fold resistance to cyclaniliprole after 26 generation selection in comparison to the initial susceptible population. The cross‐resistance experiment revealed that the low cross‐resistance to imidacloprid (4.2‐fold) in the cyclaniliprole‐selected strain was observed when comparing to the susceptible population. Realized heritability ( h 2 ) of cyclaniliprole resistance was 0.0362. When mean slope = 2.217 and h 2 = 0.0362, then 31–69 generations would be required for an increase of LC 50 s with ten times at 90%–50% selection intensity. The fecundity (the number of offspring per female) of the cyclaniliprole‐selected strain had no significant difference with the susceptible population. The mRNA expression of the target gene ryanodine receptor was significantly enhanced in the cyclaniliprole‐selected strain. The absence of fitness costs, the minimal resistance risk, and very low levels of cross‐resistance in the cyclaniliprole‐selected strain provide strong support for designing the effective management strategies against M. persicae .