痛风性关节炎
医学
尿酸
痛风
加药
药理学
高尿酸血症
关节炎
苯溴马隆
黄嘌呤氧化酶
口服
别嘌呤醇
非布索坦
新陈代谢
炎症
炎性关节炎
发病机制
内科学
作者
Ying Zhang,Jinyu Ma,Peng Zou,Minlong Xia,Siqi Wang,Bilin Jin,Zixuan Lu,Changming Zhai,Herui Huang,Yue Zhang,Hui Kong,Huihua Qu,Yan Zhao
标识
DOI:10.1016/j.intimp.2025.115805
摘要
This study demonstrates that ALRPC-CDs alleviate gouty arthritis through dual suppression of inflammatory signaling (TLR2/4-MyD88-NF-κB) and uric acid metabolism (xanthine oxidase inhibition), bridging herbal medicine and nanotechnology for multi-target therapeutic development.
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