Feeding sequence-regulated divergent (4 + 1 + 1′) annulations of α-bromo carbonyls and 1-azadienes via computational calculation-based mechanism elucidation

Based on computational calculation-based mechanism elucidation, a new controllable divergent (4 + 1 + 1′) reaction was realised by changing the feeding sequence of two different α-bromo substrates in the presence of tertiary amines and bases.