Copper‐Catalyzed Redox‐Triggered Remote CH Functionalization: Highly Selective Formation of CCF3 and CO Bonds

Abstract A Cu‐catalyzed remote sp3 CH/unactivated alkenes functionalization reaction for the concomitant construction of CCF3 and CO bonds was described. An 1,5‐H radical transfer involving an sp3 CH bond adjacent to a nitrogen atom and an α‐CF3‐alkyl radical intermediate derived from unactivated alkenes was observed and demonstrated to proceed via the radical process.