枞酸
毒力
化学
植物病害
生物
生物化学
生物技术
有机化学
树脂酸
基因
松香
作者
Pu-Ying Qi,Tai-Hong Zhang,Na Wang,Feng Yang,Dan Zhang,Wu-Bin Shao,Jiao Meng,Liwei Liu,Linhong Jin,Heng Zhang,Xiang Zhou,Song Yang
标识
DOI:10.1021/acs.jafc.2c08392
摘要
The discovery of natural product-based pesticides is critical for agriculture. In this work, a series of novel tricyclic diterpenoid derivatives decorated with an amino alcohol moiety were elaborately prepared from natural abietic acid, and their antibacterial behavior was explored. Bioassay results indicated that compound C2 exhibited the most promising bioactivity (EC50 = 0.555 μg mL-1) against Xanthomonas oryzae pv. oryzae (Xoo), about 73 times higher than the effect of commercial thiodiazole copper (TC). Results of in vivo bioassays showed that compound C2 displayed significantly higher control of rice bacterial leaf blight (curative activity: 63.8%; protective activity: 58.4%) than TC (curative activity: 43.6%; protective activity: 40.8%), and their bioactivity could be improved maximally 16% by supplementing the auxiliaries. Antibacterial behavior suggested that compound C2 could suppress various virulence factors. Overall, these findings suggested that new botanical bactericide candidates could control intractable plant bacterial diseases by suppressing virulence factors.
科研通智能强力驱动
Strongly Powered by AbleSci AI