PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma
医学
队列
内科学
免疫抑制
肿瘤科
作者
Michael R. Migden,Danny Rischin,Chrysalyne D. Schmults,Alexander Guminski,Axel Hauschild,Karl D. Lewis,Christine H. Chung,Leonel F. Hernandez‐Aya,Annette M. Lim,Anne Lynn S. Chang,Guilherme Rabinowits,Alesha Thai,Lara Dunn,Brett Hughes,Nikhil I. Khushalani,Badri Modi,Dirk Schadendorf,Bo Gao,Frank Seebach,Siyu Li
Among patients with advanced cutaneous squamous-cell carcinoma, cemiplimab induced a response in approximately half the patients and was associated with adverse events that usually occur with immune checkpoint inhibitors. (Funded by Regeneron Pharmaceuticals and Sanofi; ClinicalTrials.gov numbers, NCT02383212 and NCT02760498 .).