自愈水凝胶
材料科学
伤口敷料
万古霉素
抗菌活性
复合材料
高分子化学
金黄色葡萄球菌
细菌
遗传学
生物
作者
Yun Tang,Xinrui Shu,Guandi He,Yuhan Zhang,Yonghe Zhao,Hudie Yuan,Jingjie Yu,Jiabao Guo,Qiang Chen
摘要
-(methylol acrylamide)) functional components that could impart self-peeling and sustainable antibacterial properties. SEM images showed that the prepared hydrogel possessed a porous microstructure and the homogeneous distribution of GNs in its network. Excellent swelling ratios and thermal-induced self-peeling characteristics were confirmed by qualitative analysis. The GNs not only enhanced the strain at break of the hydrogel, but also acted as drug carriers to slow down the drug release from the hydrogel, achieving sustainable antibacterial properties and balanced biocompatibility. Therefore, this vancomycin-loaded hydrogel with self-peeling characteristics provides an effective way of preventing wound infection and can be used as a novel platform for wide-ranging applications of wound dressings.
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