Diabetes mellitus(DM) is a kind of common chronic metabolic disease with the prevalence rate of 9.7% in China,and it is easy to cause complications,disability and death.The abnormal glucose metabolism includes three types,including simple impaired fasting glucose(IFG),simple impaired glucose tolerance(IGT),IFG complicated with IGT,which are collectively referred to as the impaired glucose regulation(IGR),it is the intermediate state between normal glucose tolerance(NGT) and DM,and is known as the prediabetes,which is considered to be the inevitable stage of DM.The prevalence rate of IGR reaches 15.5%.Therefore,stoppingprediabetes from advancing from DM brooks no delay.Research shows that the appropriate lifestyle intervention and drug therapy in prediabetes can obviously delay and prevent DM in majority of patients with prediabetes.In order to prevent prediabetes from becoming DM,it is essential to combine the education,blood glucose monitoring,diet control,proper exercise,psychological guidance and drug therapy when necessary.