Inside Cover: Formation of 2‐Acyloxazoles by a Multipathway Coupled Domino Strategy: One‐Pot Metal‐Free Oxidative Cyclization Applicable to Various Substrates (Asian J. Org. Chem. 8/2013)
Domino Reactions An efficient, metal-free, multipathway coupled domino strategy for the construction of 2-acyloxazoles from various substrates, which include methyl ketones, arylethenes, and arylacetylenes, is described by An-Xin Wu and co-workers in their Full Paper on page 638 ff. This process is a logical approach by a consecutive iodination/Kornblum oxidation/cyclization sequence. This transformation is an example of the self-organization and logical synthesis of organic compounds and derivatives in domino, cascade, and tandem reactions.