脂肪组织
生物
激素
肥胖
内分泌学
功能(生物学)
性二态性
内科学
生理学
生物信息学
进化生物学
医学
作者
Olgert Bardhi,Biff F. Palmer,Deborah J. Clegg
标识
DOI:10.1098/rstb.2022.0207
摘要
Oestrogens are sex steroid hormones that have gained prominence over the years owing to their crucial roles in human health and reproduction functions which have been preserved throughout evolution. One of oestrogens actions, and the focus of this review, is their ability to determine adipose tissue distribution, function and adipose tissue 'health'. Body fat distribution is sexually dimorphic, affecting males and females differently. These differences are also apparent in the development of the metabolic syndrome and other chronic conditions where oestrogens are critical. In this review, we summarize the different molecular mechanisms, pathways and resulting pathophysiology which are a result of oestrogens actions in and on adipose tissues. This article is part of a discussion meeting issue 'Causes of obesity: theories, conjectures and evidence (Part I)'.
科研通智能强力驱动
Strongly Powered by AbleSci AI