Sunday 28 August 2016

BACKGROUND: Non-dipper patterns blood pressure is associated with increased risk of organ damage and cardiovascular disease in patients with hypertension (HT). PURPOSE:The aim of the present study is to investigate the left ventricular function and peripheral vascular arterial stiffness in hypertension patients with different blood pressure (BP) patterns. METHODS:A total of 154 hypertension patients with different BP patterns were enrolled.Patients were divided into two groups: 55 patients with dipper pattern and 99 patients with non-dipper pattern.Detail transthoracic echocardiograms were performed and analyzed with advance speckle tracking 3-orthogonal direction strain analysis for systolic function and tissue Doppler derived E/e' for diastolic function assessment.Cardio ankle vascular index (CAVI) was used to assess arterial stiffness. RESULTS:Compared with patients with dipper pattern, patients with non-dipper pattern have more impaired LV diastolic and systolic function and peripheral arterial stiffness.After multivariable analysis, non-dipper blood pressure pattern is an independent risk factor for LV systolic and diastolic function.