药物输送
药品
生物利用度
生物流体
纳米-
色谱法
化学
纳米技术
药理学
材料科学
医学
复合材料
作者
Şerife Evrim Kepekçi Tekkeli,Mustafa Volkan Kızıltaş
标识
DOI:10.2174/1568026616666161222112305
摘要
In nano drug formulations the mechanism of release is a critical process to recognize controlled and targeted drug delivery systems. In order to gain high bioavailability and specificity from the drug to reach its therapeutic goal, the active substance must be loaded into the nanoparticles efficiently. Therefore, the amount in biological fluids or tissues and the remaining amount in nano carriers are very important parameters to understand the potential of the nano drug delivery systems. For this aim, suitable and validated quantitation methods are required to determine released drug concentrations from nano pharmaceutical formulations. Keywords: HPLC, Nano Drug delivery systems, Nano carriers, Drug release, Biological fluids, Pharmaceutical preparations.
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