医学
黑色素瘤
布雷斯洛厚度
淋巴血管侵犯
病理
病态的
前哨淋巴结
有丝分裂指数
辅助
转移
内科学
癌症
细胞生物学
哲学
语言学
癌症研究
乳腺癌
有丝分裂
生物
作者
Robert G Walton,Jinah Kim,Cruz Velasco,Susan M. Swetter
出处
期刊:Cutis
日期:2014-11-01
卷期号:94 (5): 226-30
被引量:3
摘要
Measurement of tumor volume may be a helpful adjunct to established prognostic factors in cutaneous melanoma, including Breslow depth, presence or absence of ulceration, mitotic index, lymphovascular invasion, and microsatellites. This report expands on the theory that a tumor volume cutoff point of 250 mm³ as measured by surface area of the lesion (ie, longest vertical and horizontal measurements either based on clinical or gross pathological assessment) multiplied by the Breslow depth could serve as a potentially relevant predictor of sentinel lymph node (SLN) metastasis in both thin and thick invasive cutaneous melanomas, which prompted investigation of a larger sample size using the pathology database at our institution.
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