Objective To investigate the effects of mifepristone on the climacteric dysfunctional uterine bleeding in patients with clinical use and curative effect.Methods In recent years,our hospital out-patient treatment of 136 patients with gynecological Palace blood menopausal patients were retrospectively analyzed.Results 136 patients a course of treatment,effective in 121 cases,11 cases improved,with a total effective rate was 97.06%.Conclusion Mifepristone menopause Palace blood is effective and safe and reliable.Palace of blood for the treatment of menopausal effective drug,worthy to be popularized and applied.