小分子
表型筛选
表型
计算生物学
化学基因学
化学生物学
生物
遗传学
基因
标识
DOI:10.1038/nchembio.1206
摘要
Small-molecule phenotypic screening has high potential in the discovery of new chemical probes and new biological small-molecule targets. This commentary will discuss the basic principles underlying the design of phenotypic screens and propose some guidelines to facilitate the discovery of small molecules from phenotypic screens.
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