Role of Mongolian Medicine Garidisan on Rat Ulcerative Colitis

Objective:To investigate the treatment effect of garidisan on rat ulcerative colitis.Methods:The rat model of ulcerative colitis is induced by immune method and TNBS.From the macrography and microscopic evaluation identified the pharmacodynamics of garidisan on rats ulcerative colitis.Results:.Animal disease activity index,the colon mucosal damage index,histopathological score of treatment group showed statistical significance comparing with model group.The results of HE showed that there were still typical ulcer in model group,other treatment group mucosal repaired well.Conclusion:The garidisan can effectively cure the rat ulcerative colitis.its role is identical with positive drug sulfasalazine and Bupiyichang.