Covalent Organic Frameworks with Molecular Electronic Modulation as Metal‐Free Electrocatalysts for Efficient Hydrogen Peroxide Production

Tuning the electronic property of active center to balance the adsorption ability and reactivity of oxygen is essential for achieving 2e − oxygen reduction reaction (ORR) for electrocatalytic synthesis of hydrogen peroxide (H 2 O 2 ), still represents a grand challenge. Herein, different by‐design building blocks are introduced to regulate the electronic structure of catalytically active centers in covalent organic frameworks (COFs). Theoretical calculation reveals that adsorption ability of oxygen molecule (O 2 ) can be finely tuned by the regulation of electronic structure and the binding strength of O 2 is positively correlated with the electron donating ability of active center. As a result, the newly designed TP‐TD‐COF shows higher 2e − ORR activity and selectivity owing to the stronger electron donating ability and the higher adsorption strength of O 2 on electron‐rich active center. This study reveals fundamental structure – activity relationship in H 2 O 2 synthesis and offers a strategy for designing metal‐free COF catalysts through rational modulation of their electronic properties at molecular level.