Peripheral Immune-Inflammatory Parameters in Parkinson’s Disease. Dependence on the Stage of Progression

Breg cells in the patients with PD increased regardless of the disease stage. Thus, the obtained results indicate differences in the cellular and molecular immune parameters in the patients with PD and in the healthy individuals, which are dependent on the stage of the disease. These data are important for understanding molecular basis of PD development and prognosis of its course, and may be useful in identifying biomarkers of the disease severity and developing new treatment approaches depending on the stage of the disease.