吩噻嗪
化学
组合化学
分子
量子化学
立体化学
计算化学
有机化学
药理学
生物
作者
Venkatesan Kasi,K. Ashok Kumar,A. Sivakumar
标识
DOI:10.1002/slct.202302613
摘要
Abstract Phenothiazines are antipsychotic drugs that have been studied for millennia. In addition to its fundamental neuroleptic properties, phenothiazines have attracted study attention for their anticancer properties. To develop powerful anticancer medications, we have concentrated on a variety of phenothiazine designs. In this study, we used a single step multicomponent reaction of N ‐alkyl‐3‐formyl phenothiazine under reflux/ultrasonic conditions to produce a range of heterocyclic derivatives containing phenothiazine molecules. To characterize the structures of novel compounds, IR, 1 H‐NMR, 13 C‐NMR, and mass spectral data were utilized. Utilizing different cancer cell proteins, all the derivatives were investigated for their potential as anticancer molecules.
科研通智能强力驱动
Strongly Powered by AbleSci AI