黄嘌呤氧化酶
高尿酸血症
痛风
化学
非布索坦
尿酸
别嘌呤醇
氧化应激
酶
药理学
生物化学
内科学
医学
作者
Shiyang Zhou,Gangliang Huang
标识
DOI:10.1002/cbdv.202300005
摘要
Abstract The natural products have a new chemical structure and biological active diversity, so they are favored by scientific researchers. Gout is a high incidence and high‐risk disease, and the current treatments are not satisfactory. Xanthine oxidase (XO) is a key enzyme responsible for the development and progression of various metabolic and oxidative stress‐related diseases. Excessive activity of XO leads to elevated serum urate levels, which in turn leads to the development of hyperuricemia. This review mainly introduces the recent progress of the new research on the anti‐gout activity of natural products that could provide new treatment methods for gout and information for the discovery and development of new anti‐gout drugs.
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