Fusarium wilt of banana is considered as one of the most destructive worldwide diseases of banana,caused by Fusarium oxysporum f.sp.Cubense,a kind of soil epiphyte,and is badly endangering the production of banana,which arises extensive attentions and researches,but the understanding of the molecular pathogenic mechanism is not still clear.This review focused on the infection process of Fusarium oxysporum f.sp.cubenes,the components of pathotoxin,pathogenic genes of Fusarium oxysporum,the disease resistance of banana,and control of Fusarium wilt of banana.These attempted to make a systematical view on pathogenesis of fusarium wilt of banana,which would be helpful for the set of new prevention method.