Improved radioiodine-131 imaging of prostatic carcinoma using the sodium iodide symporter gene under control of the survivin promoter.

I uptake of tumor-to-muscle ratios were more prominent on day 2 (15.23 ± 4.55) and day-9 (9.78 ± 2.34) compared to the day 16 (1.29 ± 0.49), which showed a gradual reduction (P<0.05). Therefore, the Ad-Sur-NIS transfection allowed PC-3 tumor imaging by iodine-131 with an optimal time no later than 9 days post-transfection.